Request for proposals : Regulatory support consultancy for the use of human infection studies to accelerate coronavirus vaccine licensureby Editorial team
This article, published in The Lancet Infectious Diseases, presents the ethical issues associated with human challenge studies and COVID-19.
The third coronavirus outbreak in the past 20 years, the SARS-CoV-2 pandemic has caused unprecedented morbidity, mortality, and economic disruption. Safe, effective, and deployable SARS-CoV-2 vaccines are urgently needed to mitigate the consequences of the pandemic and protect from future outbreaks. The accelerated response to Covid-19 includes investments in preclinical and clinical testing and manu- facture of multiple vaccine candidates, with efficacy trials in the United States anticipated to start in July 2020.